Approval requirements
The requirements for approval by NHS Research Ethics Committees and other bodies, depending on the type of research and where it will take place.
Before you apply to a REC
See a summary of the ethical review process and the timelines involved, before you apply.
Applying using IRAS
Applications for ethical review are now made using the Integrated Research Applications System (IRAS).
Booking your REC application
How, where and when to book your application for ethical review by an NHS Research Ethics Committee.
Submitting your REC application
Where to submit your application if there are site-specific assessment considerations.
After submission
What happens after you have submitted your application.
Attending a REC meeting
What to expect when you attend the REC meeting.
After ethical review
Find out how to resubmit your application or appeal against an unfavourable decision, as well as which reports and notifications you will need to submit during and after the period of the research study, in After ethical review.
Providing feedback
We welcome feedback from applicants at all stages of the ethical review process.
Guidance
Collected guidance relating to the ethical review process.
Frequently asked questions
FAQs about the NHS ethical review process.
Glossary
A glossary of terms, acronyms and abbreviations used in the text.
